Professor Jon B Suzuki DDS PhD MBA
Jon B Suzuki is Professor of Microbiology and Immunology (School of Medicine) and Professor of Periodontology and Oral Implantology (School of Dentistry) at Temple University, Philadelphia, USA. He also serves as the Chairman and Director of Periodontology and Oral Implantology at Temple University. Professor Suzuki has served as Dean of the University of Pittsburgh, USA and as immediate past Chairman of the Food and Drug Administration Dental Products Panel.
Bisphosphonates, oral and intravenous, play a critical role in the remodelling of bone in patients with osteoporosis and low bone density. In addition to post-menopausal females and older males, clinical medical research has identified several additional groups at risk for osteoporosis. These include those with multiple myeloma, breast carcinoma, prostate carcinoma, gastric hyper acidity.
Clinical dental implications of bisphosphonates (now referred to as “anti resorptive agents”), are now well recognised. Oral lesions, diagnosed as “osteonecrosis of the jaw” (ONJ) have significant consequences.
This lecture describes the clinical S&S of ONJ with guidelines of patient medication history of bisphosphonate use and patient risk factors. Recommendations (American Dental Association, November, 2011) and diagnosis for ONJ will be discussed. Current treatment approaches and available tests will be critically appraised and prevention strategies including drug holidays will be discussed.